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Organism (ORGA)
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last updated: 26 Nov 2025
Organism information
Komagataella phaffii
Kingdom Fungi
Phylum Ascomycota
Class Saccharomycetes
Order Saccharomycetales
Family Saccharomycetaceae
Genus Komagataella
Species phaffii
  • Pichia pastoris
  • Pichia pseudopastoris
  • Yeast
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  • Budding yeast
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Fungi
Characteristics related to biosafety
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 Komagataella phaffii is a non-pathogenic, obligate aerobic budding yeast. As a methylotrophic species, it can grow on methanol as its sole carbon and energy source. 
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It was originally isolated from tree exudates in North America.
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  • Bioreactors
  • Pharmaceutical
  • Research
Additional Information
  1.  The genus Komagataella was first established in 1995 to reclassify Pichia pastoris based on marker gene sequence divergence. Strains previously known as Pichia pastoris were reassigned mainly to Komagataella pastoris and  Komagataella phaffii
  2.  The widely studied wild-type strain of Pichia pastoris, CBS7435, is now classified as Komagataella phaffii
  3.  Although the updated taxonomy is widely accepted, the name Pichia pastoris remains commonly used in the context of recombinant protein production. 
  4. Type of Komagataella phaffii Kurtzman BCCM MUCL 46514 Source: BCCM/MUCL - Agro-food & Environmental Fungal Collection
  5. Reference genome: ASM2700v1 Unit for Molecular Glycobiology, Department for Molecular Biomedical Research, VIB, UGent, Belgium (2009). Strain: GS115.
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Living Modified Organism Recipient Organism or Parental Organisms 1