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Living Modified Organism (LMO)
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Herbicide-tolerant, insect-resistant cotton
EN
GHB614 x LLCotton25 x 15985
Yes
BCS-GHØØ2-5 × ACS-GHØØ1-3 × MON-15985-7
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Organization:Bayer Crop Science K.K ()Marunouchi Kitaguchi Building, 1-6-5, MarunouchiChiyoda-ku, Tokyo
, JapanPhone:Fax:Email:
The stacked cotton line was generated through the traditional cross breeding of parental lines GHB614, LLCotton25 and 15985 to express the cry1A(c), cry2A(b), 2mepsps and the bar genes. The expression of these genes confers resistance against lepidoptera pests and tolerance to glyphosate and glufosinate herbicides.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
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BCH-ORGA-SCBD-12080-6 Organism Gossypium hirsutum (Cotton)Crops
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BCH-LMO-SCBD-14774-18 Living Modified Organism MON-15985-7 - Bollgard II™ cottonMonsanto | Resistance to antibiotics (Streptomycin), Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths)), Selectable marker genes and reporter genes
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BCH-LMO-SCBD-46334-8 Living Modified Organism BCS-GHØØ2-5 - GlyTol™ Cotton GHB614Bayer CropScience | Resistance to herbicides (Glyphosate)
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BCH-LMO-SCBD-14851-7 Living Modified Organism ACS-GHØØ1-3 - Liberty Link™ cottonBayer CropScience | Resistance to herbicides (Glufosinate)
EN
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BCS-GHØØ2-5 × ACS-GHØØ1-3 - GlyTol™ Liberty Link™ cotton| Resistance to herbicides (Glufosinate, Glyphosate)
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ACS-GHØØ1-3 × MON-15985-7 - Liberty Link™ Bollgard II™ cotton| Bayer CropScience | Resistance to antibiotics (Streptomycin), Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths)), Resistance to herbicides (Glufosinate)
PV-GHBK11, PV-GHBK04, pTEM2 and pGSV71
EN
- Cross breeding
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Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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BCH-GENE-SCBD-46333-8 5-enolpyruvylshikimate-3-phosphate synthase | Zea mays (Maize, Corn, MAIZE)Protein coding sequence | Resistance to herbicides (Glyphosate)
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BCH-GENE-SCBD-14972-12 Phosphinothricin N-acetyltransferase gene | Streptomyces hygroscopicus (STRHY)Protein coding sequence | Resistance to herbicides (Glufosinate)
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BCH-GENE-SCBD-14986-6 Cry1Ac | Bacillus thuringiensis (Bt, Bacillus, BACTU)Protein coding sequence | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths))
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BCH-GENE-SCBD-14988-7 Cry2Ab2 | Bacillus thuringiensis (Bt, Bacillus, BACTU)Protein coding sequence | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths))
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BCH-GENE-SCBD-100366-6 CaMV Enhanced 35S promoter | Cauliflower mosaic virus (CaMV)Promoter
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BCH-GENE-SCBD-103901-2 HSP 70 5' untranslated leader sequence | Petunia hybrida (Petunia, PETHY)Leader
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BCH-GENE-SCBD-100365-6 Chloroplast transit peptide 2 | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)Transit signal
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BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)Terminator
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BCH-GENE-SCBD-103856-6 α' subunit of β-conglycinin gene terminator | Glycine max (Soybean, Soya bean, Soya, SOYBN)Terminator
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BCH-GENE-SCBD-15001-5 Neomycin Phosphotransferase II | Escherichia coli (ECOLX)Protein coding sequence | Resistance to antibiotics (Kanamycin)
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BCH-GENE-SCBD-46004-7 Beta-glucuronidase coding sequence | Escherichia coli (ECOLX)Protein coding sequence | Selectable marker genes and reporter genes
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BCH-GENE-SCBD-104647-3 Histone H4 gene Promoter | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)Promoter
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BCH-GENE-SCBD-104648-2 Histone H3 Gene II intron 1 | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)Intron
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BCH-GENE-SCBD-101419-4 Optimized Transit PeptideTransit signal
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BCH-GENE-SCBD-104646-4 Histone H4 gene 3' UTR | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)Terminator
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BCH-GENE-SCBD-100287-7 CaMV 35S promoter | Cauliflower mosaic virus (CaMV)Promoter
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BCH-GENE-SCBD-15033-8 3"(9)-O-aminoglycoside adenyltransferase | Escherichia coli (ECOLX)Protein coding sequence | Resistance to antibiotics (Streptomycin)
DNA insert from 15985 vector PV-GHBK11
The T-DNA from this vector contributed the coding sequences of the cry2A(b) and uidA genes. These allow for the expression of the insecticidal cry2A(b) crystal protein which protects against lepidoptera pests and the Beta-Glucuronidase selectable marker.
DNA insert from 15985 vector PV-GHBK04
Originally integrated into the MON531 line and persisted through to the 15985 line. The T-DNA from this vector contains the coding sequence of the cry1A(c) gene and the nptII resistance gene. The aadA gene was also integrated into the host genome however it is not expressed.
DNA insert from GHB614 vector pTEM2
Cotton event GHB614 contains a stably integrated 2mepsps gene. This modification confers to the protein a decreased binding affinity for the herbicide glyphosate, allowing it to maintain sufficient enzymatic activity and thus tolerance in its presence.
DNA insert from LLCotton25 vector pGSV71
Cotton tolerant to glufosinate ammonium herbicide produced by inserting a modified phosphinothricin acetyltransferase (PAT) encoding gene (bar) from the soil bacterium Streptomyces hygroscopicus.
For additional information on this LMO, please refer to the records of the parental LMOs.
EN
The T-DNA from this vector contributed the coding sequences of the cry2A(b) and uidA genes. These allow for the expression of the insecticidal cry2A(b) crystal protein which protects against lepidoptera pests and the Beta-Glucuronidase selectable marker.
DNA insert from 15985 vector PV-GHBK04
Originally integrated into the MON531 line and persisted through to the 15985 line. The T-DNA from this vector contains the coding sequence of the cry1A(c) gene and the nptII resistance gene. The aadA gene was also integrated into the host genome however it is not expressed.
DNA insert from GHB614 vector pTEM2
Cotton event GHB614 contains a stably integrated 2mepsps gene. This modification confers to the protein a decreased binding affinity for the herbicide glyphosate, allowing it to maintain sufficient enzymatic activity and thus tolerance in its presence.
DNA insert from LLCotton25 vector pGSV71
Cotton tolerant to glufosinate ammonium herbicide produced by inserting a modified phosphinothricin acetyltransferase (PAT) encoding gene (bar) from the soil bacterium Streptomyces hygroscopicus.
For additional information on this LMO, please refer to the records of the parental LMOs.
EN
- Food
- Feed
- Fiber/textile
- BCS-GHØØ2-5 - EU Reference Laboratory for GM Food and Feed (EURL-GMFF) [ English ]
- ACS-GHØØ1-3 - EU Reference Laboratory for GM Food and Feed (EURL-GMFF) [ English ]
- MON-15985-7 - EU Reference Laboratory for GM Food and Feed (EURL-GMFF) [ English ]
- ACS-GHØØ1-3 - EU Reference Laboratory for GM Food and Feed (EURL-GMFF) ( JRC ) [ English ]
- BCS-GHØØ2-5 - EU Reference Laboratory for GM Food and Feed (EURL-GMFF) ( JRC ) [ English ]
- MON-15985-7 - EU Reference Laboratory for GM Food and Feed (EURL-GMFF) ( JRC ) [ English ]
- BCS-GHØØ2-5 - CropLife International Detection Methods Database ( CropLife ) [ English ]
- ACS-GHØØ1-3 - CropLife International Detection Methods Database ( CropLife ) [ English ]
- MON-15985-7 - CropLife International Detection Methods Database ( CropLife ) [ English ]
EN
EN
- BCS-GHØØ2-5 × ACS-GHØØ1-3 × MON-15985-7.pdf [ English ]
- GHB614 × LLCotton25 × 15985.pdf [ English ]
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