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Living Modified Organism
(LMO)
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Potato modified for 2-deoxyglucose resistance
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3 independent lines
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- Organization: Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) | BCH-CON-DE-49376-2Organization:Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)Academic or research instituteCorrensstrasse 3Gatersleben,
06466 , GermanyPhone: +49 (0)39482 5-0,Fax: +49 (0)39482 5139,Email: info@ipk-gatersleben.de,
Potato plans were modified to constitutively express 2-deoxyglucose-6-phosphate phosphatase (DOGR1) gene from Saccharomyces cerevisiae.
The function of the DOGR1 is the dephosphorylation of 2-deoxyglucose-6-phosphate in the transformed plant cells, therefore inhibiting its competitiveness with glucose-6-phosphate, which would cause cell death through the inhibition of glycolysis, protein synthesis, cell wall polysaccharide synthesis and also protein glycosylation.
Therefore, as a result of the genetic modification, the plant cells are tolerant to 2-deoxyglucose in the growth medium.
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The function of the DOGR1 is the dephosphorylation of 2-deoxyglucose-6-phosphate in the transformed plant cells, therefore inhibiting its competitiveness with glucose-6-phosphate, which would cause cell death through the inhibition of glycolysis, protein synthesis, cell wall polysaccharide synthesis and also protein glycosylation.
Therefore, as a result of the genetic modification, the plant cells are tolerant to 2-deoxyglucose in the growth medium.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
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BCH-ORGA-SCBD-12106-6 Organism Solanum tuberosum (Potato, SOLTU)Crops
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Derivative of pBIN19
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- Agrobacterium-mediated DNA transfer
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Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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BCH-GENE-SCBD-100287-7 CaMV 35S promoter | Cauliflower mosaic virus (CaMV)Promoter
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BCH-GENE-SCBD-111081-2 2-deoxyglucose-6-phosphate phosphatase 1 | Saccharomyces cerevisiae (Yeast, YEASX)Protein coding sequence | Changes in physiology and/or production,Selectable marker genes and reporter genes
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BCH-GENE-SCBD-100271-5 Octopine Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)Terminator
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BCH-GENE-SCBD-100270-6 Nopaline Synthase Gene Promoter | Agrobacterium tumefaciens (Agrobacterium)Promoter
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BCH-GENE-SCBD-15001-5 Neomycin Phosphotransferase II | Escherichia coli (ECOLX)Protein coding sequence | Resistance to antibiotics (Kanamycin)
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BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)Terminator
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- Research
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| Record type | Field | Record(s) | |
|---|---|---|---|
| Country's Decision or any other Communication | LMO identification | 1 | |
| Risk Assessment generated by a regulatory process | Living modified organism(s) | 1 | |
