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Genetic element
(GENE)
last updated: 23 Dec 2025
Coproporphyrinogen-III oxidase
EN
-
CS-hem13-KOMPAEN
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CPG oxidaseEN
-
CPOXEN
CS-hem13-PICPA
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-106439-4 Organism Komagataella pastoris (Yeast)Fungi
EN
Coproporphyrinogen-III oxidase
EN
Coproporphyrinogen III oxidase (CPOX) is a oxygen-dependent enzyme that catalyzes the oxidative decarboxylation of the propionate side chains on rings A and B of COPROGEN (coproporphyrinogen-III) yielding the corresponding vinyl groups of PROTOGEN (protoporphyrinogen-IX). This step is essential for the proper production of heme. Without the action of Coproporphyrinogen-III oxidase, the pathway would be blocked, and protoporphyrinogen-IX (and ultimately heme) would not be synthesized.
EN
EN
- Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris [ English ]
- Heme and Hemoproteins [ English ]
- Heme Biosynthesis [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 1 | |
| Living Modified Organism | Genetic elements construct | 1 | |
