Potato modified for reduced tuber amino acids content | BCH-LMO-SCBD-111458 | Living Modified Organism | Biosafety Clearing-House

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Living Modified Organism (LMO)
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BCH-LMO-SCBD-111458-1   |   PDF   |   Print   |  
Decisions on the LMO Risk Assessments  
last updated: 11 Nov 2016
Living Modified Organism identity
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Potato modified for reduced tuber amino acids content
EN
StAAP2/12, StAAP2/18, StAAP2/27, StAAP2/38, StAAP2/44, StAAP2/48, StAAP2/150 to StAAP2/180
No
A fragment of the gene coding for the amino acid permease 2 from Solanum tuberosum, which is expressed predominantly in stems, is constitutively expressed in an antisense orientation in the transgenic potato plants.

As a result of the genetic modification, the production of endogenous amino acid permease is inhibited thereby leading to a reduction in amino acid transport to the tubers and, consequently, resulting in a reduction in the content of soluble nitrogen compounds in the tubers.

Even though some anti-AAP2 lines demonstrate a significant reduction in StAAP2 mRNA in the stems, they do not show any changes in regard to the Nitrogen/Carbon ratio, amino acid composition or the carbohydrate content in the tubers.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
EN
  • Potato modified for reduced tuber amino acids content
    | Eberhard Karls Universität Tübingen | Changes in quality and/or metabolite content (Protein and amino acids), Resistance to antibiotics (Kanamycin)
Characteristics of the modification process
Derivative of pBIN19
EN
  • Agrobacterium-mediated DNA transfer
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-100287-7 CaMV 35S promoter | Cauliflower mosaic virus (CaMV)
    Promoter
  • BCH-GENE-SCBD-111295-1 Amino acid permease 2 gene | Solanum tuberosum (Potato, SOLTU)
    Protein coding sequence | Changes in quality and/or metabolite content (Protein and amino acids)
  • BCH-GENE-SCBD-100271-5 Octopine Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)
    Terminator
  • BCH-GENE-SCBD-100270-6 Nopaline Synthase Gene Promoter | Agrobacterium tumefaciens (Agrobacterium)
    Promoter
  • BCH-GENE-SCBD-15001-5 Neomycin Phosphotransferase II | Escherichia coli (ECOLX)
    Protein coding sequence | Resistance to antibiotics (Kanamycin)
  • BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)
    Terminator
EN
LMO characteristics
EN
  • Research
Detection method(s)
EN
Additional Information
EN
Records referencing this document Show in search
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Country's Decision or any other Communication Living modified organism(s) 1
Risk Assessment generated by a regulatory process Living modified organism(s) 1
Living Modified Organism Related LMO(s) 1