Potato modified for resistance against Potato Virus Y | BCH-LMO-SCBD-111460 | Living Modified Organism | Biosafety Clearing-House

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BCH-LMO-SCBD-111460-1   |   PDF   |   Print   |  

Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
last updated: 21 Nov 2016
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Potato modified for resistance against Potato Virus Y
EN
GPTV-Kan-NIb Linda Nb11, GPTV-Kan-NIb Linda Nb12
No
The genetically modified potato plants constitutively express a mutated fragment of the NIb gene of the Potato Virus Y, which, in its native form, codes for a RNA-dependent RNA polymerase. The modification is expected to confer resistance to PVY.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
EN
  • Potato modified for resistance against Potato Virus Y
    | Bundesanstalt für Züchtungsforschung an Kulturpflanzen(BAZ) | Resistance to antibiotics (Kanamycin), Resistance to diseases and pests (Viruses, Potato virus Y (PVY)), Selectable marker genes and reporter genes
Characteristics of the modification process
pGPTV-Kan-NIb
EN
  • Agrobacterium-mediated DNA transfer
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-100287-7 CaMV 35S promoter | Cauliflower mosaic virus (CaMV)
    Promoter
  • BCH-GENE-SCBD-111452-1 Nuclear inclusion protein b gene | Potato virus Y (PVY)
    Protein coding sequence | Resistance to diseases and pests (Viruses, Potato virus Y (PVY))
  • BCH-GENE-SCBD-100290-6 CaMV 35S terminator | Cauliflower mosaic virus (CaMV)
    Terminator
  • BCH-GENE-SCBD-46004-7 Beta-glucuronidase coding sequence | Escherichia coli (ECOLX)
    Protein coding sequence | Selectable marker genes and reporter genes
  • BCH-GENE-SCBD-100270-6 Nopaline Synthase Gene Promoter | Agrobacterium tumefaciens (Agrobacterium)
    Promoter
  • BCH-GENE-SCBD-15001-5 Neomycin Phosphotransferase II | Escherichia coli (ECOLX)
    Protein coding sequence | Resistance to antibiotics (Kanamycin)
  • BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)
    Terminator
A mutated sequence of the NIb replicase of the Potato Virus Y is expressed under the control of the 35S promoter and termination sequence of the Cauliflower Mosaic Virus.

The mutated sequence has a deletion at the C-terminus (approx. 400 nt) and at the N-terminus (6 nt), and an internal shift in the reading frame affecting 14 amino acids, leading to a non-functional gene product.
EN
LMO characteristics
EN
  • Research
Detection method(s)
EN
Additional Information
EN
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