BCS-GHØØ2-5 × BCS-GHØØ4-7 × BCS-GHØØ5-8 - GlyTol™ x TwinLink™ Cotton | BCH-LMO-SCBD-104649 | Living Modified Organism | Biosafety Clearing-House

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Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
last updated: 21 Jan 2014
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
GlyTol™ x TwinLink™ Cotton
EN
GHB614 x T304-40 x GHB119
Yes
BCS-GHØØ2-5 × BCS-GHØØ4-7 × BCS-GHØØ5-8
The stacked cotton line GlyTol™ x TwinLink™ was created through the conventional cross-breeding of the LM cotton lines GHB614, T304-40 and GHB119 to express Cry1Ab and Cry2Ae each of which expresses insecticidal crystal proteins thus conferring resistance against lepidoptera and 2mepsps and the bar gene which confer tolerance to the herbicides glyphosate and glufosinate, respectively.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
  • BCH-ORGA-SCBD-12080-6 Organism Gossypium hirsutum (Cotton)
    Crops
  • BCH-LMO-SCBD-46334-8 Living Modified Organism BCS-GHØØ2-5 - GlyTol™ Cotton GHB614
    Bayer CropScience | Resistance to herbicides (Glyphosate)
  • BCH-LMO-SCBD-101018-13 Living Modified Organism BCS-GHØØ4-7 - Herbicide-tolerant, insect-resistant cotton
    Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths), European corn borer (Ostrinia nubilalis)), Resistance to herbicides (Glufosinate)
  • BCH-LMO-SCBD-101898-5 Living Modified Organism BCS-GHØØ5-8 - Herbicide-tolerant and lepidoptera-resistant cotton
    Bayer BioScience N.V. | Changes in quality and/or metabolite content (Pigmentation / Coloration), Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths), Cotton bollworm (Helicoverpa spp.), Fall armyworm (Spodoptera frugiperda)), Resistance to herbicides (Glufosinate)
EN
  • BCS-GHØØ4-7 × BCS-GHØØ5-8 - TwinLink™ Cotton
    | Bayer Schering Pharma | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths), Cotton bollworm (Helicoverpa spp.), European corn borer (Ostrinia nubilalis), Fall armyworm (Spodoptera frugiperda)), Resistance to herbicides (Glufosinate)
Characteristics of the modification process
pTEM2, pTDL008 and pTEM12
EN
  • Cross breeding
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-14985-12 Cry1Ab | Bacillus thuringiensis (Bt, Bacillus, BACTU)
    Protein coding sequence | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths))
  • BCH-GENE-SCBD-101895-8 Cry2Ae | Bacillus thuringiensis (Bt, Bacillus, BACTU)
    Protein coding sequence | Resistance to diseases and pests (Insects, Lepidoptera (butterflies and moths), Cotton bollworm (Helicoverpa spp.), Fall armyworm (Spodoptera frugiperda))
  • BCH-GENE-SCBD-46333-8 5-enolpyruvylshikimate-3-phosphate synthase | Zea mays (Maize, Corn, MAIZE)
    Protein coding sequence | Resistance to herbicides (Glyphosate)
  • BCH-GENE-SCBD-104647-3 Histone H4 gene Promoter | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)
    Promoter
  • BCH-GENE-SCBD-104648-2 Histone H3 Gene II intron 1 | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)
    Intron
  • BCH-GENE-SCBD-101419-4 Optimized Transit Peptide
    Transit signal
  • BCH-GENE-SCBD-104646-4 Histone H4 gene 3' UTR | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)
    Terminator
  • BCH-GENE-SCBD-101025-5 NADP-malic enzyme 1 gene 3'UTR and terminator | Flaveria bidentis (Coastal plain yellowtops, FLABI)
    Terminator
  • BCH-GENE-SCBD-101021-3 Ps7s7 | Subterranean clover stunt virus (SCSV, Subterranean clover stunt virus)
    Promoter
  • BCH-GENE-SCBD-100287-7 CaMV 35S promoter | Cauliflower mosaic virus (CaMV)
    Promoter
  • BCH-GENE-SCBD-14972-12 Phosphinothricin N-acetyltransferase gene | Streptomyces hygroscopicus (STRHY)
    Protein coding sequence | Resistance to herbicides (Glufosinate)
  • BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)
    Terminator
  • BCH-GENE-SCBD-101900-6 CsVMV promoter | Cassava vein mosaic virus (Cassava vein mosaic virus, CVMV, CsVMV)
    Promoter
  • BCH-GENE-SCBD-101901-3 5' untranslated leader of chlorophyll a/b-binding protein | Petunia hybrida (Petunia, PETHY)
    Leader
  • BCH-GENE-SCBD-101902-4 rbcS Transit Peptide | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)
    Transit signal
  • BCH-GENE-SCBD-100290-6 CaMV 35S terminator | Cauliflower mosaic virus (CaMV)
    Terminator
  • BCH-GENE-SCBD-104947-3 5'e1 Leader | Oryza sativa (Rice, ORYSA)
    Leader
DNA insert from GHB614 vector pTEM2
Contains a single copy of the 2mepsps gene and regulatory elements which confers tolerance to the herbicide glyphosate

DNA insert from T304-40 vector pTDL008
Contains one full copy and partial elements of the Cry1Ab gene which expressed an insecticidal crystal protein that protects against lepidopteran pests and the bar gene which confers tolerance to the herbicide glufosinate.

DNA insert from GHB119 vector pTEM12
Contains one full copy of the Cry2Ae gene which expressed an insecticidal crystal protein that protects against lepidopteran pests and the bar gene which confers tolerance to the herbicide glufosinate.

For additional information on this LMO, please refer to the records of the parental LMOs.
EN
LMO characteristics
EN
  • Food
  • Feed
  • Fiber/textile
Additional Information
EN
Records referencing this document Show in search
Record type Field Record(s)
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