DAS-59122-7 × MON-ØØ6Ø3-6 - Herculex™ RW Rootworm Protection Roundup Ready™ 2 maize | BCH-LMO-SCBD-15178 | Living Modified Organism | Biosafety Clearing-House


Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
last updated: 24 Jul 2013
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Herculex™ RW Rootworm Protection Roundup Ready™ 2 maize
59122 x NK603
DAS-59122-7 × MON-ØØ6Ø3-6
The stacked maize line 59122 x NK603 was produced by cross breeding between maize LMOs 59122 and NK603 to resist the Coleopteran pests (western corn rootworm, northern corn rootworm and Mexican corn rootworm) and for tolerance to herbicides containing glufosinate and glyphosate.

59122 x NK603 inherited the cry34Ab1, cry35Ab1 and pat genes from the 59122 parent, and two copies of the epsps gene from NK603
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
  • BCH-ORGA-SCBD-246-6 Organism Zea mays (Maize, Corn, MAIZE)
  • BCH-LMO-SCBD-15165-13 Living Modified Organism DAS-59122-7 - Herculex™ RW Rootworm Protection maize
    Pioneer Hi-Bred International Inc. | Resistance to diseases and pests (Insects, Coleoptera (beetles)), Resistance to herbicides (Glufosinate)
  • BCH-LMO-SCBD-14776-17 Living Modified Organism MON-ØØ6Ø3-6 - Roundup Ready™ maize
    Monsanto | Resistance to herbicides (Glyphosate)
Characteristics of the modification process
PV-ZMGT32 and PHP17662
  • Cross breeding
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
DNA insert from 59122 vector PHP17662:
The cry34Ab1 and cry35Ab1 genes, isolated from the common soil bacterium Bacillus thuringiensis (Bt) strain PS149B1, produce the insect control proteins (delta-endotoxins) Cry34Ab1 and Cry35Ab1.

The pat gene was isolated from the soil bacterium Streptomyces viridochromogenes and confers tolerance to herbicides containing glufosinate ammonium.

DNA insert from NK603 vector PV-ZMGT32:
59122 x NK603 also contains a form of the plant enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) that allows the plant to survive the otherwise lethal application of glyphosate. The glyphosate-tolerant EPSPS gene was isolated from the CP4 strain of the common soil bacterium Agrobacterium tumefaciens.

For additional information on this LMO, please refer to the records of the parental LMOs.
LMO characteristics
  • Food
  • Feed
  • Biofuel
Additional Information